Cortisol And Diabetes
How Cortisol & Chronic Stress Raise Diabetes Risk A clear, evidence-forward explanation • December 6, 2025 The connection between cortisol, stress, and diabetes is real and well-established in medical science. Below is a concise but detailed breakdown of the mechanisms, real-world impact, and practical ways to lower cortisol to protect metabolic health. How cortisol (the main stress hormone) contributes to diabetes When you're under prolonged stress (physical or emotional), your adrenal glands pump out cortisol continuously. That sustained elevation of cortisol affects blood sugar and insulin in several important ways: Increases glucose production (gluconeogenesis): Cortisol stimulates the liver to create new glucose even when it’s not needed, raising blood sugar. Causes insulin resistance: Muscle and fat c...